| Coaches | |
|---|---|
| Position | Name |
| Head Coach | Jim Harbaugh |
| Offensive Coordinator | Greg Roman |
| Defensive Coordinator | Jesse Minter |
| Special Teams Coach | Ryan Ficken |
| Offense | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | NO | Player 4 | NO | Player 5 |
| QB | 10 | Justin Herbert | 5 | Trey Lance | ||||||
| RB | 8 | Omarion Hampton(R) | 22 | Najee Harris | 28 | Hassan Haskins | ||||
| LWR | 9 | Tre Harris(R) | 84 | KeAndre Lambert-Smith(R) | ||||||
| SWR | 15 | Ladd McConkey | 12 | Derius Davis | ||||||
| RWR | NA | Keenan Allen | 1 | Quentin Johnston | ||||||
| TE | 89 | Will Dissly | 83 | Tyler Conklin | 86 | Oronde Gadsden II(R) | 42 | Tucker Fisk | ||
| FB | 44 | Scott Matlock | ||||||||
| LT | 76 | Joe Alt | 76 | Austin Deculus | ||||||
| LG | 77 | Zion Johnson | ||||||||
| C | 75 | Bradley Bozeman | 78 | Andre James | ||||||
| RG | 73 | Mekhi Becton | 68 | Jamaree Salyer | ||||||
| RT | 79 | Trey Pipkins | ||||||||
| Defense | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | NO | Player 4 | NO | Player 5 |
| DE | 91 | Da'Shawn Hand | 92 | Justin Eboigbe | 44 | Scott Matlock | ||||
| DT | 93 | Otito Ogbonnia | 96 | Naquan Jones | ||||||
| NT | 90 | Teair Tart | 99 | Jamaree Caldwell(R) | ||||||
| LOLB | 45 | Tuli Tuipulotu | 54 | Kyle Kennard(R) | 50 | Caleb Murphy | ||||
| LILB | 6 | Denzel Perryman | 43 | Troy Dye | ||||||
| RILB | NA | Daiyan Henley | 58 | Marlowe Wax(R) | ||||||
| ROLB | 52 | Khalil Mack | 48 | Bud Dupree | ||||||
| LCB | 26 | Donte Jackson | 46 | Nikko Reed(R) | ||||||
| RCB | 20 | Cam Hart | 24 | Benjamin St-Juste | 39 | Eric Rogers(R) | ||||
| SS | 3 | Derwin James | 27 | R.J. Mickens(R) | ||||||
| FS | 32 | Alohi Gilman | 2 | Elijah Molden | 40 | Kendall Williamson | ||||
| NB | 29 | Tarheeb Still | 36 | Ja'Sir Taylor | ||||||
| Special Teams | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | ||||
| P | 16 | J.K. Scott | ||||||||
| K | 11 | Cameron Dicker | ||||||||
| PR | 12 | Derius Davis | 15 | Ladd McConkey | 84 | KeAndre Lambert-Smith(R) | ||||
| KR | 12 | Derius Davis | 28 | Hassan Haskins | 84 | KeAndre Lambert-Smith(R) | ||||
| H | 16 | J.K. Scott | ||||||||
| KO | 11 | Cameron Dicker | ||||||||
